Uterine fluid lipidomic as an endometrial receptivity predictive tool

Genomic, proteomic and lipidomic evaluation of endometrial receptivity

Endometrial receptivity is a complex phenomenon that plays a vital role in infertility. Although quality of embryo can be evaluated for a successful implantation, endometrial receptivity is still an unknown factor. With advances in technology, the microarray approach has provided an 'omic' tool to evaluate endometrial receptivity. In Latin, 'omic' means the whole family. The genomic, proteomic,...

Endometrial markers of uterine receptivity utilizing the donor oocyte model.

BACKGROUND Ethical constraints limit the ability to study peri-implantation phase human endometrium. In this study, the donor oocyte model was used to study candidate endometrial markers of uterine receptivity. METHODS Archived, paraffin-embedded tissue obtained by endometrial biopsy during cycle days 21-23 of patients undergoing 'mock' hormonal treatment cycles were evaluated by standard his...

I-28: Uterine Receptivity

Endometrial Receptivity and its Predictive Value for IVF/ICSI-Outcome.

Endometrial receptivity plays a crucial role in the establishment of a healthy pregnancy in cycles of assisted reproduction. The endometrium as a key factor during reproduction can be assessed in multiple ways, most commonly through transvaginal grey-scale or 3-D ultrasound. It has been shown that controlled ovarian hyperstimulation has a great impact on the uterine lining, which leads to diffe...

Redefining Endometrial Receptivity

However, the notion of receptivity as a static state in which the tissue is poised, frozen in time, awaiting the arrival of an adequately developed embryo, is naïve. An integrative definition of receptivity must embrace communication between maternal and embryonic tissues. At receptivity, the endometrium has reached a point at which negotiation can begin that may or may not lead to successful i...